Circadian relationship of serum uric acid and nitric oxide.
نویسندگان
چکیده
To the Editor: Nitric oxide–mediated damage has been implicated in a number of neurological diseases including stroke1, 2 and multiple sclerosis (MS).3 For instance, monocytes expressing high levels of nitric oxide synthetase have been found in plaques from the brains of patients with MS.4 The proximal agent of neuronal cell damage may be peroxynitrite, which is formed in vivo from the synthesis of nitric oxide and superoxide.
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عنوان ژورنال:
- JAMA
دوره 283 17 شماره
صفحات -
تاریخ انتشار 2000